Jiang Chang, Ph.D.


Professor Jiang Chang, University of Chinese Academy of Sciences, Wenzhou Institute, Fellow of International Union of Societies for Biomaterials Science and Engineering (FBSE), Fellow of Royal Society of Chemistry (FRSC), and Fellow of American Institute of Medical and Biological Engineering (AIMBE). Ph.D in 1991 in Chemistry from the Technical University of Darmstadt in Germany. Post Doctoral Research Fellow at the Medical University of Luebeck in Germany (1991-1993); Research fellow at the School of Medicine, University of Auckland in New Zealand (1993-1997); Research Assistant Professor in the Medical School at New York University (1997-1999); Research scientist at Johnson&Johnson, New Jersey, USA (1999-2000); Professor and founder of the Biomaterials and Tissue Engineering Research Center of the Shanghai Institute of Ceramics (2000-2020). Visiting Researcher, Queensland University of Technology, Institute of Health and Biomedical Innovation (2010.01), Visiting Fellow, Queensland University of Technology, School of Chemistry, Physics and Mechanical Engineering, Faculty of Science and Engineering (2013.06), Visiting Professor, Tokyo Institute of Technology, School of Materials Science (2016.01-03).

Professor Chang is the vice president of the Interdisciplinary Research Society for Bone and Joint Injectable Biomaterials. He is also an associate editor of the Journal of Materials Chemistry B, and International Editorial Advisory Board member of Biomaterials. His research focuses on bioactive materials for tissue regeneration and tissue engineering and the mechanisms of the interaction between biomaterials and cells. Professor Chang has over 400 scientific papers published in international peer-reviewed scientific journals with more than 20000 citations and H-index 77, and 55 patents.

Selected Publications


  1. Lu Zheng, Dongyuan Lü, Fan Zhang, Min Xing, Xiaoya Wang, Xiaohua Ji, Xinyu Shu, Peiwen Li, Shouqin Lü, Jiang Chang*, Mian Long*. Regulation of hepatic differentiation of human embryonic stem cells by calcium silicate extracts for liver injury repairing. Applied materials today 2020, 20:100730
  2. Lili Sheng, Zhaowenbin Zhang, Yu Zhang, Endian Wang, Bing Ma, Qing Xu, Lingling Ma, Meng Zhang, Ge Pei, Jiang Chang*. A novel “hot spring”-mimetic hydrogel with excellent angiogenic properties for chronic wound healing. Biomaterials 2020, 264,120414.
  3. Feng Bao, Ge Pei, Zhongcao Wu, Hui Zhuang, Zhaowenbin Zhang, Zhiguang Huan, Chengtie Wu, Jiang Chang*. Bioactive self-pumping composite wound dressings with micropore array modified Janus membrane for enhanced diabetic wound healing. Advanced Functional Materials (2020) DOI:10.1002/adfm.202005422 (IF=16.836)
  4. Lingling Ma, Yanling Zhou, Zhaowenbin Zhang, Yaqin Liu, Dong Zhai, Hui Zhuang, Qin Li, Jianding Yuye, Chengtie Wu, Jiang Chang*. Multi-functional bioactive Nd-Ca-Si glasses for fluorescent thermometry, photothermal therapy and burn tissue repair. Science Advances, 2020, 6:eabb1311(1-11) (IF=12.804)
  5. Qing Xu, Mengling Chang, Yu Zhang, Endian Wang, Min Xing, Long Gao, Zhiguang Huan, Feng Guo*, Jiang Chang*. PDA/Cu bioactive hydrogel with “hot ions effect” for inhibition of drug-resistant bacteria and enhancement of infectious skin wound healing. ACS Applied Materials & Interfaces, 2020, 12, 31255-31269. DOI: 10.1021/acsami.0c08890 (IF=8.456)
  6. Long Gao, Min Yi, Min Xing, Hekai Li, Yanling Zhou, Qing Xu, Zhaowenbin Zhang, Zhanpeng Wen, Jiang Chang*. In situ activated mesenchymal stem cell (MSCs) by bioactive hydrogel for myocardial infarction treatment. Journal of Materials Chemistry B. (2020).
  7. Zhaowenbin Zhang, Qiuxia Dai, Yu Zhang, Hui Zhuang, Endian Wang, Qing Xu, Lingling Ma, Chengtie Wu, Zhiguang Huan, Feng Guo*, Jiang Chang*. Design of a Multifunctional Biomaterial Inspired by Ancient Chinese Medicine for Hair Regeneration in Burned Skin. ACS Applied Materials & Interfaces 12:12489-12499 (2020) (IF=8.456)
  8. Fangfang Wang, Xiaoya Wang, Kui Ma, Cuiping Zhang*, Jiang Chang*, Xiaobing Fu*. Akermanite bioceramic enhances wound healing with accelerated reepithelialization by promoting proliferation, migration, and stemness of epidermal cells. Wound repair and regeneration 28(1):16-25 (2020) (IF=2.85)
  9. 高龙,张赵文斌,常江*. 生物玻璃/聚乳酸多孔微球的制备及其作为细胞载体的研究.无机材料学报 Accepted (2020) (IF=0.635)
  10. 王晓亚,常江*,生物陶瓷在组织工程中的应用,生命科学 32(3):257-266 (2020) (中文核心期刊)
  11. Xiaocheng Wang, Jianmin Xue, Bing Ma, JinFu Wu, Jiang Chang, Michael Gelinsky, Chengtie Wu*. Black Bioceramics: Combining regeneration with therapy. Advanced Materials 2020; DOI: 10.1002/adma.202005140
  12. Siyu Ni#, Dong Zhai#, Zhiguang Huan, Tinglin Zhang, Jiang Chang, Chengtie Wu *. Nanosized concave pit/convex dot microarray for immunomodulatory osteogenesis and Angiogenesis Nanoscale, 2020, 12, 16474-16488.
  13. Meng Zhang, Rongcai Lin, Xin Wang, Jianmin Xue, Cuijun Deng, Chun Feng, Hui Zhuang, Jingge Ma, Chen Qin, Li Wan, Jiang Chang, Chengtie Wu*. 3D printing of Haversian bone–mimicking scaffolds for multicellular delivery in bone regeneration. Science Advances 2020, 6: eaaz6725 (1-12) (IF=12.804)
  14. Bing Ma#, Wentao Dang#, Zhibo Yang, Jiang Chang, Chengtie Wu*. MoS2 nanoclusters-based biomaterials for disease-impaired wound therapy. Applied Materials Today, 20 (2020) 100735. (2020) (IF=8.013)
  15. Yaqin Liu, Rongcai Lin, Lingling Ma, Hui Zhuang, Jiang Chang, Chengtie Wu*. Mesoporous bioactive glass for synergistic therapy of tumor and regeneration of bone tissue. Applied Materials Today 19:100578 (1-14) (2020) (IF=8.013)
  16. Wentao Dang#, Bing Ma#, Bo Li#, Zhiguang Huan, Nan Ma, Haibo Zhu, Jiang Chang, Yin Xiao, Chengtie Wu*. 3D printing of metal-organic framework nanosheets-structured scaffolds with tumor therapy and bone construction. Biofabrication 12(2):025005 (1-18) (2020) (IF=7.236)
  17. Tian Li, Jiang Chang, Yufang Zhu*, Chengtie Wu*. 3D Printing of Bioinspired Biomaterials for Tissue Regeneration. Advanced Healthcare Materials (2020) DOI:10.1002/adhm.202000208 (IF=6.27)
  18. Tian Li#, Bing Ma#, Jianmin Xue, Dong Zhai, Pengyu Zhao, Jiang Chang, Chengtie Wu*. Bioinspired Biomaterials with a Brick-and-Mortar Microstructure Combining Mechanical and Biological Performance. Advanced Healthcare Materials 9(4):1901211 (1-9) (2020) (IF=6.27)
  19. Xiaoya Wang, Meng Zhang, Jingge Ma, Mengchi Xu,Jiang Chang,Chengtie Wu*, 3D printing of cell containers-like scaffolds for multi-cells tissue engineering, Engineering (2020) (IF=4.568)
  20. Chun Feng, Bing Ma, Mengchi Xu, Dong Zhai, Yin Liu, Jianmin Xue, Jiang Chang, Chengtie Wu*. 3D printing of scaffolds with synergistic effects of micro-nano surface and hollow channels for bone regeneration. ACS Biomaterials Science & Engineering (2020) DOI:10.1021/acsbiomaterials.9b01824 (IF=4.511)


  1. Yanling Zhou, Chengtie Wu, Jiang Chang*, Bioceramics to regulate stem cells and their microenvironment for tissue regeneration, Materials Today, 2019 (20), 41-56.
  2. Yu Zhang, Mengling Chang, Feng Bao, Min Xing, Endian Wang, Qing Xu, Zhiguang Huan, Feng Guo* and Jiang Chang*, Multifunctional Zn doped hollow mesoporous silica/polycaprolactone electrospun membranes with enhanced hair follicle regeneration and antibacterial activity for wound healing, Nanoscale, 2019, 11, 6315–6333
  3. Xiaocheng Wang#, Bing Ma#, Jianmin Xue, JinFu Wu, Jiang Chang, Chengtie Wu*. Defective Black Nano-Titania Thermogels for Cutaneous Tumor-Induced Therapy and Healing. Nano Letters 2019,19:2138-2147.
  4. Hongshi Ma,# Quan Zhou,# Jiang Chang, Chengtie Wu*. Grape Seed-Inspired Smart Hydrogel Scaffolds for Melanoma Therapy and Wound Healing. ACS Nano 2019,13(4):4302-4311.
  5. Cuijun Deng, Rongcai Lin, MengZhang, Chen Qin, Qingqiang Yao*, Liming Wang, Jiang Chang, Chengtie Wu*. Micro/nanometer-Structured Scaffolds for Regeneration of both Cartilage and Subchondral Bone. Advanced Functional Materials 2019,29;4:1806068(1-15).
  6. Tian Li, Dong Zhai, Bing Ma, Jianmin Xue, Pengyu Zhao, Jiang Chang,Michael Gelinsky, Chengtie Wu*.3D Printing of Hot Dog-Like Biomaterials with Hierarchical Architecture and Distinct Bioactivity. Advanced Science 2019, 1901146 (1-8).
  7. Qingqing Yu, Yiming Han, Tian Tian, Quan Zhou, Zhengfang Yi, Jiang Chang, Chengtie Wu*.Chinese sesame stick-inspired nano-fibrous scaffolds for tumor therapy and skin tissue reconstruction. Biomaterials 2019, 194:25–35.
  8. Lei Chen#, Cuijun Deng#, Jiayi Li, Qingqiang Yao*, Jiang Chang*, Liming Wang, Chengtie Wu*.3D printing of a lithium-calcium-silicate crystal bioscaffold with dual bioactivities for osteochondral interface reconstruction. Biomaterials 2019,196:138-150.
  9. Lu Liu#, Yaqin Liu#, Chun Feng, Jiang Chang, Runqing Fu, Tingting Wu, Fei Yu, Xiaoting Wang, Lunguo Xia*, Chengtie Wu*, Bing Fang*. Lithium-containing biomaterials stimulate bone marrow stromal cell-derived exosomal miR-130a secretion to promote angiogenesis. Biomaterials 2019,192:523-536.
  10. Wentao Dang#, Bing Ma#, Zhiguang Huan, Rongcai Lin, Xiaoya Wang, Tian Li, JinFu Wu, Nan Ma, Haibo Zhu, Jiang Chang, Chengtie Wu*. LaB6 surface chemistry-reinforced scaffolds for treating bone tumors and bone defects. Applied Materials Today, 2019, 16, 42-55.
  11. Qian Zhang#, Lei Chen#, Bin Chen, Changxing Chen, Jiang Chang, Yin Xiao, Chengtie Wu*, Fuhua Yan*. Lithium-calcium-silicate bioceramics stimulating cementogenic/osteogenicdifferentiation of periodontal ligament cells and periodontal regeneration. Applied Materials Today 2019,16: 375–387 .
  12. Yaqin Liu#, Qingqing Yu#, Jiang Chang, Chengtie Wu*, Nanobiomaterials: from 0D to 3D for tumor therapy and tissue regeneration. Nanoscale, 2019, 11:13678-13708.
  13. Qingqing Yu, Jiang Chang, Chengtie Wu*. Silicate bioceramics: from soft tissue regeneration to tumor therapy. Journal of Materials Chemistry B. 2019, 7: 5449-5460 .
  14. Cuijun Deng, Jiang Chang, Chengtie Wu*. Bioactive scaffolds for osteochondral regeneration. Journal of Orthopaedic Translation. 2019,17:15-25.
  15. Jianmin Xue, Xiaocheng Wang, Endian Wang, Tian Li, Jiang Chang, Chengtie Wu*. Bioinspired Multifunctional Biomaterials with Hierarchical Microstructure for Wound Dressing. Acta Biomaterialia 2019,100:270-279.
  16. Min Yi#, Hekai Li#, Xiaoya Wang, Jianyun Yan, Long Gao, Yinyan He, Xinglong Zhong, Yanbin Cai, Weijing Feng, Zhanpeng Wen, Chengtie Wu, Caiwen Ou*, Jiang Chang*, Minsheng Chen*. Ion Therapy: A Novel Strategy for Acute Myocardial Infarction. Advanced Science. 2019,6(1):1801260 (1-17).
  17. Chen Yang, Cancan Zhao, Xiaoya Wang, Mengchao Shi, Yanlun Zhu, Linguo Jing, Chengtie Wu, Jiang Chang*. Stimulation of Osteogenesis and Angiogenesis by Micro/Nano Hierarchical Hydroxyapatite via Macrophage Immunomodulation. Nanoscale. 2019,11:17699–17708.
  18. Long Gao, Yanling Zhou, Jinliang Peng, Chen Xu, Qing Xu, Min Xing, Jiang Chang*. A Novel Dual-adhesive and Bioactive Hydrogel Activated by Bioglass for Wound Healing. NPG Asia Materials 2019,11:66(1-11)
  19. Chen Xu, Bing Ma, Jinliang Peng, Long Gao, Yuhong Xu, Zhiguang Huan, Jiang Chang*. Tricalcium silicate/graphene oxide bone cement with photothermal properties for tumor ablation. Journal of Materials Chemistry B. 2019, 7:2808-2818.
  20. Yanlun Zhu#, Lingzhi Kong#, Fatemeh Farhadi, Wei Xia, Jiang Chang, Yaohua He*, Haiyan Li*. An injectable continuous stratified structurally and functionally biomimetic construct for enhancing osteochondral regeneration. Biomaterials 2019, 192:149–158.
  21. Nan Ma#, Bing Ma#, Yangling Zhou,Haibo Zhu, Ying Zhou, Zhiguang Huan,Peiji Wang, Jiang Chang*. In vivo evaluation of the subchronic systemic toxicity of akermanite bioceramic for bone regeneration following ISO standard methods. RSC Advances. 2019, 9, 17530-17536.


  1. Xiaoya Wang, Long Gao, Yan Han, Min Xing, Cancan Zhao, Jinliang Peng, and Jiang Chang*, Silicon-Enhanced Adipogenesis and Angiogenesis for Vascularized Adipose Tissue Engineering, Advanced Science. 2018,1800776
  2. Xiaotong Wang, Changzheng Wei*, Bin Cao, Lixia Jiang, Yongtai Hou, and Jiang Chang, Fabrication of Multiple-Layered Hydrogel Scaffolds with Elaborate Structure and Good Mechanical Properties via 3D Printing and Ionic Reinforcement, ACS Appl. Mater. Interfaces, 2018, DOI: 10.1021/acsami.8b04116 Publication Date (Web): May 2, 2018
  3. Yu Zhang, Cui Huang,* and Jiang Chang,* Ca-doped mesoporous SiO2/dental resin composites with enhanced mechanical properties, bioactivity and antibacterial properties, Journal of Materials Chemistry B 2018, 6:477-486
  4. Yang Zhou, Di Chang, Jiang Chang. Preparation of nano-structured pig bone hydroxyapatite for high efficiency adsorption of Pb2+ from aqueous solution. International Journal of Applied Ceramic Technology. In Press (2018).
  5. Hongshi Ma,# Tao Li,# Zhiguang Huan, Meng Zhang, Zezheng Yang, Jinwu Wang,* Jiang Chang, Chengtie Wu*. 3D Printing of high-strength bioscaffolds for synergistic therapy of bone cancer. NPG Asia Materials 2018,10:31-44
  6. Cuijun Deng, Qiang Yang, Xiaolei Sun, Lei Chen, Chun Feng, Jiang Chang, Chengtie Wu*. Bioactive scaffolds with Li and Si ions-synergistic effects for osteochondral defects regeneration. Applied Materials Today 2018, 10:203-216
  7. Zetao Chen, Shengwei Han, Mengchao Shi, Guanqi Liu, Zhuofan Chen, Jiang Chang, Chengtie Wu*, Yin Xiao*. Immunomodulatory effects of mesoporous silica nanoparticles on osteogenesis: from nanoimmunotoxicity to nanoimmunotherapy. Applied Materials Today 2018,10:184-193
  8. Chen Xu#, Yang Wen#, Yanling Zhou, Yaqin Zhu, Yuandong Dou, Zhiguang Huan*, Jiang Chang*. In vitro self-setting properties, bioactivity, and antibacterial ability of a silicate-based premixed bone cement. International Journal of Applied Ceramic Technology. 2018, 15(2):460-471.
  9. Yaqin Liu#, Tao Li#, Hongshi Ma, Dong Zhai, Cuijun Deng, Jinwu Wang, Shangjun Zhuo, Jiang Chang, Chengtie Wu*. 3D-printed scaffolds with bioactive elements-induced photothermal effect for bone tumor therapy, Acta Biomaterialia (2018)
  10. Wentao Dang, Tao Li, Bo Li, Hongshi Ma, Dong Zhai, Xiaocheng Wang, Jiang Chang, Yin Xiao, Jinwu Wang*, Chengtie Wu*. A bifunctional scaffold with CuFeSe2 nanocrystals for tumor therapy and bone reconstruction. Biomaterials 2018,160:92-106
  11. Cuijun Deng, Huiying Zhu, Jiayi Li, Chun Feng, Qingqiang Yao, Liming Wang, Jiang Chang, Chengtie Wu*. Bioactive Scaffolds for Regeneration of Cartilage and Subchondral Bone Interface. Theranostics 2018, 8(7):1940-1955
  12. Yan Huang #, Chengtie Wu #, Xiaoling Zhang, Jiang Chang* Kerong Dai*. Regulation of immune response by bioactive ions released from silicate bioceramics for bone regeneration. Acta Biomaterialia 2018, 66:81-92.
  13. Yang Zhou, Yanling Zhou, Long Gao, Chengtie Wu, Jiang Chang*, Synthesis of artificial dental enamel by an elastin-like polypeptide assisted biomimetic approach. Journal of Materials Chemistry B. 2018,6:844-853
  14. Chen Xu, XiaoYa Wang, Jie Zhou, Zhiguang Huan*, Jiang Chang*, Bioactive tricalcium silicate/alginate composite bone cements with enhanced physicochemical properties. Journal of Biomedical Materials Research: Part B – Applied Biomaterials, 2018, 106B:237-244
  15. Yanling Zhou, Chen Xua, Xiaoya Wang, Yuandong Dou, Zhiguang Huan*, Jiang Chang*, Fast setting tricalcium silicate/magnesium phosphate premixed cement for root canal filling. Ceramics International. 2018,44:3015-3023
  16. Qingqing Yu#, Yiming Han#, Xiaocheng Wang, Chen Qin, Dong Zhai, Zhengfang Yi*, Jiang Chang, Yin Xiao, Chengtie Wu*. Copper Silicate Hollow Microspheres-Incorporated Scaffolds for Chemo-Photothermal Therapy of Melanoma and Tissue Healing. ACS Nano, 2018, 12:2695-2707
  17. Chen Yang, Zhiguang Huan, Xiaoya Wang, Chengtie Wu, Jiang Chang*. 3D Printed Fe Scaffolds with HA Nanocoating for Bone Regeneration. ACS Biomaterials Science & Engineering. 2018,4:608-616
  18. Cuijun Deng, Huiying Zhu, Jiayi Li, Chun Feng, Qingqiang Yao, Liming Wang, Jiang Chang, Chengtie Wu. Bioactive Scaffolds for Regeneration of Cartilage and Subchondral Bone Interface. Theranostics. 2018, 8(7):1940-1955
  19. Cuijun Deng#, Qiang Yang#, Xiaolei Sun, Lei Chen, Chun Feng, Jiang Chang, Chengtie Wu*. Bioactive scaffolds with Li and Si ions-synergistic effects for osteochondral defects regeneration. Applied Materials Today 2018,10:203-216
  20. Jianmin Xue, Chun Feng, Lunguo Xia, Dong Zhai, Bing Ma, Xiaocheng Wang, Bing Fang, Jiang Chang, Chengtie Wu, Assembly Preparation of Multilayered Biomaterials with High Mechanical Strength and Bone- Forming Bioactivity. Chemistry of Materials 2018, 30(14):4646-4657
  21. Wentao Dang#, Xiaoya Wang#, Jiayi Li, Cuijun Deng, Yaqin Liu, Qingqiang Yao, Liming Wang, Jiang Chang, Chengtie Wu*. 3D printing of Mo-containing scaffolds with activated anabolic responses and bi-lineage bioactivities. Theranostics 2018, 8(16): 4372-4392
  22. Bo Li, Xiaoya Wang, Lei Chen, Yanling Zhou, Wentao Dang, Jiang Chang, Chengtie Wu*.Ultrathin Cu-TCPP MOF nanosheets: a new theragnostic nanoplatform with magnetic resonance/near-infrared thermal imaging for synergistic phototherapy of cancers. Theranostics 2018,8(15):4086-4096
  23. Lingzhi Kong#, Zhi Wu#, Huakun Zhao, Haomin Cui, Ji Shen, Jiang Chang, Haiyan Li*, Yaohua He*. Bioactive Injectable Hydrogels Containing Desferrioxamine and Bioglass for Diabetic Wound Healing. ACS Applied Materials & Interfaces 2018, 10:30103?30114
  24. Hongshi Ma, Chun Feng, Jiang Chang, Chengtie Wu*. 3D-printed bioceramic scaffolds: From bone tissue engineering to tumor therapy. Acta Biomaterialia. 2018,79:37–59
  25. Cancan Zhao, Xiaoya Wang, Long Gao, Linguo Jing, Quan Zhou, Jiang Chang*.The role of the micro-pattern and nano-topography of hydroxyapatite bioceramics on stimulating osteogenic differentiation of mesenchymal stem cells. Acta Biomaterialia 2018,73: 509–521
  26. Min Xing, Xiaoya Wang, Endian Wang, Long Gao, Jiang Chang*. Bone tissue engineering strategy based on the synergistic effects of silicon and strontium ions. Acta Biomaterialia 2018, 72: 381–395
  27. Yanling Zhou, Long Gao, Jinliang Peng, Min Xing, Yan Han, Xiaoya Wang, Yuhong Xu, Jiang Chang*. Bioglass Activated Albumin Hydrogels for Wound Healing. Advanced Healthcare Materials 2018, 1800144
  28. Fengyu Hao, Limei Qin, Jingdong Liu, Jiang Chang, Zhiguang Huan, Lin Wu. Assessment of calcium sulfate hemihydrate–Tricalcium silicate composite for bone healing in a rabbit femoral condyle model. Materials Science & Engineering C 2018, 88:53–60
  29. Zhi Wu#, Sanguo Wang#, Jiang Chang, Zhiguang Huan*, Haiyan Li*. TiO2 nanotubes enhance vascularization and osteogenic differentiation through stimulating interactions between bone marrow stromal cells and endothelial cells. Journal of Biomedical Nanotechnology 2018,14(4):765-777
  30. Xiaocheng Wang, Jiang Chang, Chengtie Wu*. Bioactive inorganic/organic nanocomposites for wound healing. Applied Materials Today 2018, 11:308-319
  31. Yinghong Zhou#, Shengwei Han#, Lan Xiao, Pingping Han, Shengfang Wang, Jie He, Jiang Chang, Chengtie Wu*, Yin Xiao*. Accelerated host angiogenesis and immune responses by ion release from mesoporous bioactive glass. Journal of Materials Chemistry B 2018, 6: 3274-3284
  32. Xiangkai Zhang#, Yanlun Zhu#, Lingyan Cao#, Xiao Wang, Ao Zheng, Jiang Chang, Jiannan Wu, Jin Wen, Xinquan Jiang, Haiyan Li*, Zhiyuan Zhang*. Alginate-aker injectable composite hydrogels promoted irregular bone regeneration through stem cell recruitment and osteogenic differentiation. Journal of Materials Chemistry B 2018, 6: 1951-1964
  33. Shuo Chen, Zhiguang Huan, Lin Zhang*, Jiang Chang*. The clinical application of a silicate-based wound dressing (DermFactor?) for wound healing after anal surgery: A randomized study. International Journal of Surgery 2018, 52:229–232


  1. Chun Feng#, Wenjie Zhang#, Cuijun Deng, Guanglong Li, Jiang Chang, Zhiyuan Zhang, Xinquan Jiang*, Chengtie Wu*.3D Printing of Lotus Root-Like Biomimetic Materials for Cell Delivery and Tissue Regeneration. Advanced Science. 2017,4:1700401
  2. Lixia Mao#, Lunguo Xia#, Jiang Chang, Jiaqiang Liu, Lingyong Jiang, Chengtie Wu*, Bing Fang*. The synergistic effects of Sr and Si bioactive ions on osteogenesis, osteoclastogenesis and angiogenesis for osteoporotic bone regeneration. Acta Biomaterialia 2017,61:217-232
  3. Yinghong Zhou#, Mengchao Shi#, Julian R Jones, Zetao Chen, Jiang Chang, Chengtie Wu,* Yin Xiao.* Strategies to Direct Vascularisation using Mesoporous Bioactive Glass-based Biomaterials for Bone Regeneration. International Materials Reviews 2017,62(7):392-414
  4. Xiaocheng Wang, Fang Lv, Tian Li, Yiming Han, Zhengfang Yi, Mingyao Liu, Jiang Chang, Chengtie Wu*. Electrospun Micropatterned Nanocomposites Incorporated with Cu2S Nanoflowers for Skin Tumor Therapy and Wound Healing. ACS Nano. 2017, 11(11):11337-11349
  5. Cuijun Deng#, Qingqiang Yao#, Chun Feng, Jiayi Li, Liming Wang*, Guofeng Cheng, Mengchao Shi, Lei Chen, Jiang Chang, Chengtie Wu*. 3D Printing of Bi-lineage Constructive Biomaterials for Bone and Cartilage Regeneration. Advanced Functional Materials 2017, 27(36):1703117
  6. Xiaocheng Wang#, Tao Li#, Hongshi Ma, Dong Zhai, Chuan Jiang, Jiang Chang,* Jinwu Wang,* Chengtie Wu*. A 3D-Printed scaffold with MoS2 nanosheets for tumor therapy and tissue regeneration. NPG Asia Materials 2017,9:376-389
  7. Fang Lv, Jie Wang, Peng Xu, Yiming Han, Hongshi Ma, He Xu*, Shijie Chen, Jiang Chang, Qinfei Ke,Mingyao Liu, Zhengfang Yi*, Chengtie Wu*, A conducive bioceramic/polymer composite biomaterial for diabetic wound healing. Acta Biomaterialia,2017,60:128-143
  8. Mengchao Shi#, Lunguo Xia#, Zetao Chen, Fang Lv, Huiying Zhu, Fei Wei, Shengwei Han, Jiang Chang, Yin Xiao*, Chengtie Wu*. Europium-doped mesoporous silica nanosphere as an immune-modulating osteogenesis/angiogenesis agent. Biomaterials 2017,44:176-187
  9. Wenjie Zhang#, Chun Feng#, Guangzheng Yang#, Guanglong Li, Xun Ding, Shaoyi Wang, Yuandong Dou, Zhiyuan Zhang, Jiang Chang, Chengtie Wu**, Xinquan Jiang*.3D-printed scaffolds with synergistic effect of hollow-pipe structure and bioactive ions for vascularized bone regeneration. Biomaterials.2017, 135:85-95
  10. Chen Yang, Xiaoya Wang, Bing Ma, Zhiguang Huan, Nan Ma, Haibo Zhu, Chengtie Wu, and Jiang Chang*, 3D-printed bioactive Ca3SiO5 bone cement scaffolds with nano surface structure for bone regeneration, ACS Applied Materials & Interfaces 2017,9:5757-5767
  11. Zetao Chen#, Siyu Ni#, Shengwei Han, Ross Crawford, Shifeier Lu, Fei Wei, Jiang Chang, Chengtie Wu*, Yin Xiao*. Nanoporous microstructures mediate osteogenesis by modulating the osteo-immune response of macrophages. Nanoscale 2017,9:706-718
  12. Hong Li# , Jinyan Li# , Jia Jiang, Fang Lv , Jiang Chang, Shiyi Chen* , Chengtie Wu*. An osteogenesis/angiogenesis-stimulation artificial ligament for anterior cruciate ligament reconstruction. Acta Biomaterialia. 2017,54:399-410
  13. Jinyan Li#, Fang Lv#, He Xu, Yali Zhang, Jie Wang, Zhengfang Yi*, Jingbo Yin, Jiang Chang, Chengtie Wu*. A patterned nanocomposite membrane for high-efficiency healing of diabetic wound. Journal of Materials Chemistry B 2017,5:1926-1934
  14. Min Xing, Zhiguang Huan, Qin Li, Jianding Yu, Jiang Chang*, Containerless processing of Ca-Sr-Si system bioactive materials: thermophysical properties andion release behaviors, Ceramics International, 2017,43:5156-5163
  15. Yinghong Zhou#, Mengchao Shi#, Julian R Jones, Zetao Chen, Jiang Chang, Chengtie Wu,* Yin Xiao.* Strategies to Direct Vascularisation using Mesoporous Bioactive Glass-based Biomaterials for Bone Regeneration. International Materials Reviews 2017,62(7):392-414
  16. Yongliang Zhang, Dong Zhai, Mengchi Xu, Qingqiang Yao, Huiying Zhu, Jiang Chang, Chengtie Wu*. 3D-printed bioceramic scaffolds with antibacterial and osteogenic activity, Biofabrication 2017,9:025037
  17. Sina Dezfuli, Zhiguang Huan*, Ajen Mol, Sander Leeflang, Jiang Chang, Jie Zhou. Advanced bredigite-containing magnesium-matrix composites for biodegradable bone implant applications. Materials Science & Engineering C-Materials for Biological Applications 2017; 647-660.
  18. Sanguo Wang, Yachen Xu, Jie Zhou, Haiyan Li, Jiang Chang, Zhiguang Huan*. In vitro degradation and surface bioactivity of iron-matrix composites containing silicate-based bioceramic. Bioactive Mater 2017; 2:10-18.
  19. Bing Ma#, Zhiguang Huan#, Chen Xu, Nan Ma, Haibo Zhu, Jipin Zhong, Jiang Chang*. Preparation anand in vivo evaluation of a silicate-based composite bone cement. Journal of Biomaterial Applications 2017,32(2):257-264
  20. Sina Dezfulia*, Zhiguang Huan, Sander Leeflang, Jiang Chang, Jie Zhou. Fabrication of novel magnesium-matrix composites and their mechanical properties prior to and during in vitro degradation. Journal of the Mechanical Behavior of Biomedical Materials 2017, 67:74-86.
  21. Xin Dong, Jiang Chang, Haiyan Li*. Bioglass promotes wound healing through modulating the paracrine effects between macrophages and repairing cells. Journal of Materials Chemistry B, 2017, 5, 5240- 5250.
  22. Yachen Xu, Jinliang Peng, Xin Dong, Yuhong Xu, Haiyan Li*, Jiang Chang*. Combined chemical and structural signals of biomaterials synergistically activates cell-cell communications for improving tissue regeneration. Acta Biomaterialia, 2017,55: 249-261
  23. Yonghui Li#, Yan Han#, Xiaoya Wang, Jinliang Peng, Yuhong Xu, Jiang Chang*.Multi-functional hydrogels prepared by dualion crosslinking for chronic wound healing. ACS Applied Materials & Interfaces.2017,9(19):16054-16062
  24. Yan Han#, Yonghui Li#,  Qiongyu Zeng, Haiyan Li,  Jinliang Peng,  Yuhong Xu,  Jiang Chang* .Injectable bioactive akermanite/alginate composite hydrogels for  in situ skin tissue engineering. Journal of Materials Chemistry B. 2017, 5(18) :3315-3326