Sin-Yeang (Ronald) Teow
Assistant Professor
College of Science and Technology
- Email: tsinyean@kean.edu

Biography
Ronald graduated from University of Science Malaysia with PhD in Molecular Virology and Oncology. Since then, he was trained in the National Institute of Health, Institute for Medical Research Malaysia, investigating the pathogenicity of Epstein-barr virus in the development of nasopharyngeal carcinoma using multicellular and xenograft models. In 2016, he joined Sunway University, Malaysia as a research fellow and was awarded the Vice Chancellor Early Career Researcher in 2018. He was then promoted to an associate professor in 2022. Ronald is currently an assistant professor at Department of Biology, Wenzhou-Kean University, China and his current research aims in developing potent anticancer nanotherapeutics against solid tumors. He has received grants cumulatively ~RMB 3 million during his research career in Malaysia and published more than 60 peer-reviewed academic papers including 1 patent and several invited book chapters.
Education
- 2011 – 2015: PhD, University of Science Malaysia
- 2009 – 2010: BSc (Hons) in Biotechnology, University of Sunderland, UK
Academic Experience
- 2023 – present: Assistant Professor, Wenzhou-Kean University, China
- 2016 – 2022: Research Fellow to Associate Professor, Sunway University, Malaysia
- 2015 – 2016: Postdoc, NIH Institute for Medical Research, Malaysia
Courses teaching at WKU
Immunology
Molecular Biology of Cancer
Molecular Cellular Techniques
Research Interests
Cancer therapeutics (nanoparticles-based, nanocarriers, etc)
Cancer biology
Selected Publications
- Yusefi M, Shameli K, Soon MLK, Teow SY et al. (2023) Chitosan coated magnetic cellulose nanowhisker as a drug delivery system for potential colorectal cancer treatment. International Journal of Biological Macromolecules, 123388 (IF–8.025)
- Lee KX, Shameli K, Nagao Y, Yew YP, Teow SY et al. (2023) Potential use of gold-silver core-shell nanoparticles derived from Garcinia mangostana peel for anticancer compound, protocatechuic acid delivery. Frontiers in Molecular Biosciences, 16648714 (IF–6.113)
- Yusefi M, Soon MLK, Teow SY et al. (2022) Fabrication of cellulose nanocrystals as potential anticancer drug delivery systems for colorectal cancer treatment. International Journal of Biological Macromolecules, 199, 372-385 (IF–8.025)
- Ismail NA, Shameli K, Mohamad Sukri SNA, Hara H, Teow SY et al. (2022) Sonochemical synthesis of a copper reduced graphene oxide nanocomposite using honey and evaluation of its antibacterial and cytotoxic activities. Frontiers in Molecular Biosciences, 9, 995853 (IF–6.113)
- Yusefi M, Soon MLK, Shameli K, Teow SY et al. (2021) 5-fluorouracil loaded magnetic cellulose bionanocomposites for potential colorectal cancer treatment. Carbohydrate Polymers, 118523. (IF–10.723)
- Yusefi M, Shameli K, Yee OS, Teow SY, et al (2021) Green synthesis of Fe3O4 nanoparticles stabilized by a Garcinia mangostana fruit peel extract for hyperthermia and anticancer activities. International Journal of Nanomedicine 16, 2515. (IF–7.033)
- Yusefi M, Chan HY, Teow SY et al. (2021) 5-fluorouracil encapsulated chitosan-celluose fiber cellulose bionanocomposites: Synthesis, characterization and in vitro analysis towards colorectal cancer cells. Nanomaterials, 11(7), 1691. (IF–5.719)
- Yew YP, Shameli K, Mohamad SE, Lee KX, Teow SY (2020) Green synthesized montmorillonite/carrageenan/Fe3O4 nanocomposites for pH-responsive release of protocatechuic acid and its anticancer activity. International Journal of Molecular Sciences 21(14), 4851. (IF–6.208)
- Lee KX, Shameli K, Yew YP, Teow SY, et al (2020) Recent developments in the facile bio-synthesis of gold nanoparticles (AuNPs) and their biomedical applications. International Journal of Nanomedicine 15, 275. (IF – 7.033)
- Yusefi M, Shameli K, Jahangirian H, Teow SY, et al (2020) The potential anticancer activity of 5-fluorouracil loaded in cellulose fibers isolated from rice straw. International Journal of Nanomedicine 15, 5417. (IF–7.033)
- Tan HL, Kai D, Pasbakhsh P, Teow SY, et al. (2020) Electrospun cellulose acetate butyrate/polyethylene glycol (CAB/PEG) composite nanofibers: a potential scaffold for tissue engineering. Colloids and surfaces B: Biointerfaces 188, 110713. (IF–5.999)
- Izadiyan Z, Shameli K, Miyake M, Teow SY, et al (2019) Green fabrication of biologically active magnetic core-shell Fe3O4/ Au and their cytotoxic effect. Materials Science and Engineering: C. 96, 51-57. (IF–7.328)
- Ismail NA, Shameli K., Wong MMT, Teow SY, et al (2019) Antibacterial and cytotoxic effect of honey mediated copper nanoparticles synthesized using ultrasonic assistance. Materials Science and Engineering: C. 104, 109899. (IF–7.328)
- Yew YP, Shameli K, Mohamad SE, Nagao Y, Teow SY, et al (2019) Potential anticancer activity of protocatechuic acid loaded in montmorillonite/Fe3O4 nanocomposites stabilized by seaweed Kappaphycus alvarezii. International Journal of Pharmaceutics 572, 118743. (IF–6.510)
- Yap HY, Tee SZY, Wong MMT, Chow SK, Peh SC, Teow SY. (2018) Pathogenic role of immune cells in rheumatoid arthritis (RA): Implications in clinical treatment and biomarker development. Cells 7(10), 161. (IF–7.666)
Patent
Khoo ASB, Abdul Aziz N, Teow SY, et al. Isolated nasopharyngeal carcinoma cells and derivatives prepared thereof. US20210395696A1, US Patent App. 17/289, 132, 2021
Selected Research Grants
- 2022-2024 Ministry of Education Malaysia Fundamental Research Grant Scheme (FRGS/1/2022/SKK10/SYUC/02/4) ‘Elucidating determinant factors that enhance transcytosis and the anticancer efficacy of a chitosan nanogel-loaded with 5-fluorouracil in colorectal cancer’ ~RMB 260,870
- 2021-2023 Sunway-Cambridge Collaboration Fund (STR-CAMMED-SET-000-2021) ‘Low dose radiation and cellular response’ ~RMB 699,569
- 2020-2021 Sunway Internal Research Grant (GRTIN-RSF-SHMS-DMS-03-2020) ‘Generation of exosomes loaded with anticancer iron oxide nanoparticles (IONPs) for targeted delivery with hyperthermia treatment in colon cancer’ ~RMB 57,971
- 2019-2023 Ministry of Education Malaysia Fundamental Research Grant Scheme (FRGS/1/2019/SKK08/SYUC/02/1) ‘Investigating the role of SIRT1-autophagy regulatory axis in chemoresistance in hepatocellular carcinoma (HCC) using 3D tumour spheroid in vitro model’ ~RMB 272,323
- 2018-2021 Sunway Internal Research Grant 2018 (SRC/003/2017/FR) ‘Investigating the role of KRAS in autophagy in colorectal cancer (CRC) and its implications in therapy response and patient survival and the potential use of autophagy marker as CRC biomarker’ ~RMB 78,183
- 2017-2019 MAKNA Cancer Research Grant Award (EXT-SIDS-SIHD-MAKNA-2017-01) ‘Defining the role of KRAS in autophagy in colorectal cancer and implications in predicting response to therapy in advanced stage colorectal cancers and overall patient survival’ ~RMB 47,000